Goals
Scientific & Engineering Goals
- Establish novel modelling framework to examine current theories & knowledge of Alzheimer’s and neurodegeneration
- Institute common ontology to identify crucial aspects that provide linkages and interfaces between various sub-systems within complete brain architecture
- Create inventory of information about theories & comprehensive knowledge management platform
- Construct high-performance AI/ML model platform – “Modelbase” – to integrate & explore currently available conceptual knowledge & experimental data
- Develop new methods, models & algorithms to enable exploration of complex non-linear dynamics between biology, environment, disease, and public health
Scientific Goals & Plans
- Methods to improve AD clinical trial design, conduct & analysis
- New conceptual models of AD: hypothesis/perspective paper
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Target: Lancet Public Health or Lancet Digital Health
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Think-tank meeting (Las Vegas or Boston) to discuss a demonstration project for in silico model of health neurons
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- Linking with Brain Watch Coalition
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Global coalition to assure accurate, affordable, and equitable access to brain health care and treatments
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Working with PAD 2020, pharma, academia on clinical decision intelligence applications
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- Planned meetings
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2nd INDRC research conference
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CTAD panel discussion
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Using digital tools to advance AD trials
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Bioinformatics and other new platforms to expedite drug develop in AD
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